We don’t know what the global Cryptid Nation 2nd Edition print run is as of January 2nd, 2022, however, we do know that the print-run for the United States was 62,500 per product.
Knowing that the print run for Nightfall, the set that was released prior to CN2E, had a print run of 50,000 per product, with 40,000 being distributed throughout the United States, and the final 10,000 being distributed throughout the rest of the world, I am making the assumption that the global print run for CN2E is around 72,500-75,000 per product. We don’t know for sure, but it is certainly less than the 100k-250k estimates that were floating around.